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| Reactivity: | M,R & M |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | LDB3 rabbit polyclonal antibody |
Gene Name: | LIM domain-binding protein 3 |
Synonyms: | CYPHER, KIAA01613, KIAA0613, LDB3, ldb3z1, ldb3z4, LIM domain binding 3, LIM domain binding protein 3, ORACLE, PDLIM6, Protein cypher, ZASP |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse LDB3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, cytoskeleton |
Predicted MW. | 76 kDa |
Observed MW. | 76 kDa |
Uniprot ID: | Q9JKS4 |
Product Usage Information
WB | Mouse, Rat | 1: 1000-1: 4000 | skeletal muscle |
IHC/IF | Mouse | 1: 1000-1: 2000 | heart, skeletal muscle |
Background
This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules.
Images
| Western blot analysis of LDB3 (GB113897) at dilution of 1: 1000 |
| Immunohistochemistry of paraffin embedded mouse heart using LDB3 (GB113897) at dilution of 1: 2000 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse skeletal muscle using LDB3 (GB113897) at dilution of 1: 2000 (400x lens) |
| Immunofluorescence of paraffin embedded embedded mouse heart using LDB3 (GB113897) at dilution of 1: 1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
