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Anti-LEFTY2 Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | LEFTY2 rabbit polyclonal antibody |
Gene Name: | Left-right determination factor 1 |
Synonyms: | Protein lefty-1, Lefty protein, Stimulated by retinoic acid gene 3 protein, Transforming growth factor beta-4, TGF-beta-4, Lefty1, Ebaf, Lefty, Stra3, Tgfb4 |
Immunogen: | Recombinant protein corresponding to Mouse LEFTY2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 41 kDa |
Observed MW. | 34 kDa |
Uniprot ID: | O75610, Q64280 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 500-1: 1000 | spleen |
Background
Left-right determination factor 1 and 2 (Lefty1/2) belong to the TGF-beta superfamily of proteins and are responsible for determination of left-right positioning of visceral organs during embryogenesis. Lefty1 acts as a regulator of Lefty2 and NODAL as the lack of the former resulted in bilateral expression of nodal, lefty2 and Pitx2 (a homeobox gene normally expressed on the left side and blocks the signal for leftness). Lefty2 may play a role in endometrial bleeding.
Images
| Western blot analysis of Lefty2 (GB111757) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
