Reactivity: | H,M,R & H,M,R |
Applications: | IHC & IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | LITAF rabbit polyclonal |
Gene Name: | Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog |
Synonyms: | LPS-induced TNF-alpha factor homolog, Estrogen-enhanced transcript protein, mEET, LITAF-like protein, NEDD4 WW domain-binding protein 3, Litaf, N4wbp3, Tbx1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse LITAF |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 17 kDa |
Observed MW. | 24 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | spleen, placenta, brain |
IHC | Mouse, Rat | 1: 4800-1: 9600 | spleen |
Background
Lipopolysaccharide-induced TNF factor(LITAF) is a transcription factor that identified as a regulator of TNF-alpha gene expression. It may has a role in protein degradation pathways and in tumor necrosis factor alpha(TNF-alpha) gene expression. Also it may regulate the expression of the CCL2/MCP-1 chemokine through NFKB1.Defects in LITAF may be involved in extramammary Paget disease (EMPD) carcinogenesis.
Images
Western blot analysis of LITAF (GB112990) at dilution of 1: 2000 | |
Immunohistochemistry analysis of paraffin-embedded mouse spleen using LITAF (GB112990) at dilution of 1: 9600 | |
Immunohistochemistry analysis of paraffin-embedded rat spleen using LITAF (GB112990) at dilution of 1: 9600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |