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| Reactivity: | M,R & M,R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | LMX1b rabbit polyclonal |
Gene Name: | LIM homeobox transcription factor 1-beta |
Synonyms: | LMX1B, LMX1.2, NPS1, LIM homeobox transcription factor 1 beta |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse LMX1b |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 500-1: 1000 | lung, skeletal muscle, heart muscle |
IF | Mouse, Rat | 1: 250-1: 500 | lung, skeletal muscle, heart muscle |
Background
LMX1B is a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. This protein is a LIM homeobox transcription factor which plays a central role in dorso-ventral patterning of the vertebrate limb, which is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse lung using LMX1b (GB11744) at dilution of 1: 500 |
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Immunohistochemistry analysis of paraffin-embedded rat skeletal muscle using LMX1b (GB11744) at dilution of 1: 500 |
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Immunohistochemistry analysis of paraffin-embedded rat heart muscle using LMX1b (GB11744) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
