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Anti-LOXL2 Rabbit pAb (100 μl)
| Reactivity: | H & H |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | LOXL2 rabbit polyclonal antibody |
Gene Name: | Lysyl oxidase homolog 2 |
Synonyms: | Lysyl oxidase-like protein 2, Loxl2, Lysyl oxidase related protein WS9 14, Lysyl oxidase homolog 2, WS9 14 |
Immunogen: | Recombinant protein corresponding to Mouse LOXL2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm, Secreted |
Uniprot ID: | P58022, B5DF27 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 250-1: 1000 | lung, skin, testis, bone, brain |
Background
LOXL2, also named as WS9-14, belongs to an amine oxidase family whose members have been implicated in crosslink formation in stromal collagens and elastin, cell motility, and tumor development and progression. LOXL2 activity might be a crucial modulator of Snail, providing an additional control mechanism of EMT and tumor progression. Increased LOXL2 expression in colon and esophageal cancer may contribute to tumor progression.
Images
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Immunohistochemistry of paraffin embedded mouse bone using LOXL2 (GB111322) at dilution of 1:250 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse lung using LOXL2 (GB111322) at dilution of 1:250 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse skin using LOXL2 (GB111322) at dilution of 1:250 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse testis using LOXL2 (GB111322) at dilution of 1:250 (400x lens) |
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Immunohistochemistry of paraffin embedded rat bone using LOXL2 (GB111322) at dilution of 1:250 (400x lens) |
| Immunofluorescence of paraffin embedded mouse brain using LOXL2 (GB111322) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded mouse testis using LOXL2 (GB111322) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |