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Anti-Lamin A + Lamin C Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Lamin A + Lamin C rabbit polyclonal |
Gene Name: | Prelamin-A/C |
Synonyms: | LMNA, CDCD1, CDDC, CMD1A, CMT2B1 EMD2, FPL, FPLD, FPLD2, HGPS, IDC LDP1, LFP, LGMD1B, LMN1, LMNC LMNL1, PRO1, lamin A/C, MADA |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Lamin A + Lamin C |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 74 kDa |
Observed MW. | 74 kDa |
Subcellular location: | Nucleus |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | lung, heart, liver |
| IHC/IF | Human, Mouse, Rat | 1: 500-1: 800 | lung, liver |
Background
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics.
Images
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Western blot analysis of Lamin A/C (GB11407) at dilution of 1: 1000. Lane 1: Hela cell lysate Lane 2: HepG2 cell lysate Lane 3: NIH/3T3 cell lysate Lane 4: Mouse lung tissue lysate Lane 5: Mouse heart tissue lysate Lane 6: Mouse liver tissue lysate Lane 7: Rat lung tissue lysate Lane 8: Rat heart tissue lysate Lane 9: Rat liver tissue lysate |
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Immunohistochemistry analysis of paraffin-embedded human lung cancer using Lamin A/C (GB11407) at dilution of 1: 500 |
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Immunohistochemistry analysis of paraffin-embedded human liver cancer using Lamin A/C (GB11407) at dilution of 1:500 |
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Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using Lamin A/C (GB11407) at dilution of 1:500 |
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Immunohistochemistry analysis of paraffin-embedded mouse liver using Lamin A/C (GB11407)at dilution of 1:800 |
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Immunohistochemistry analysis of paraffin-embedded rat liver using Lamin A/C (GB11407) at dilution of 1:800 |
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Immunofluorescent analysis of paraformaldehyde-fixed human ovary using Lamin A/C (GB11407) at dilution of 1:800 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat liver using Lamin A/C (GB11407) at dilution of 1:800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
