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| Product Category: | Mouse lentivirus expressing Ctsd |
| Description: | Premade lentivirus for over-expression of mouse Ctsd and control, ready to use format. |
| Gene Name: | cathepsin D |
| Gene Symbol: | Ctsd |
| Synonyms: | CD; CatD |
| ACCN: | NM_009983.3 |
| Gene ID: | 13033 |
| Vector: | VP010-CMV-MCS-3×Flag-EF1-NEO |
| Fusion Tag: | HA |
| Promoter: | CMV |
| Selection Antibiotic: | Neomycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Enables aspartic-type endopeptidase activity. Involved in insulin catabolic process and insulin receptor recycling. Acts upstream of or within autophagosome assembly. Located in extracellular space and lysosome. Is active in endosome lumen. Is expressed in several structures, including central nervous system; extraembryonic component; eye; genitourinary system; and lung. Used to study neuronal ceroid lipofuscinosis 10. Human ortholog(s) of this gene implicated in Alzheimer's disease; breast cancer; and neuronal ceroid lipofuscinosis 10. Orthologous to human CTSD (cathepsin D).
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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