Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | MAP2 rabbit polyclonal antibody |
Gene Name: | Microtubule-associated protein 2 |
Synonyms: | MAP2, MAP2A, MAP2B, MAP2C, microtubule associated protein 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MAP2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 199 kDa |
Observed MW. | 280 kDa |
Uniprot ID: | P20357, P15146 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | brain |
Background
The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neuritogenesis. MAP2 serves to stabilize microtubules (MT) growth by crosslinking MT with intermediate filaments and other MTs. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described.
Images
Western blot analysis of GLI-1 MAP2 (GB11128-1) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |