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Anti-MAdCAM1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MAdCAM1 rabbit polyclonal antibody |
Gene Name: | Mucosal addressin cell adhesion molecule 1 |
Synonyms: | MAdCAM-1, mMAdCAM-1, Madcam1, Addressin mucosal, hMAdCAM 1, MACAM1, Mucosal vascular addressin cell adhesion molecule 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MAdCAM1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell Membrane |
Uniprot ID: | Q61826, O70540 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 3000 | appendix, colon, lung+LPS, pancreas+LPS, pancreatic, small intestine |
Background
MAdCAM-1 is an immunoglobulin (Ig) cell adhesion molecule family member. MAdCAM-1 is involved in lymphocyte homing to mucosal sites and is expressed on high endothelial venules (HEV) of both mesenteric lymph nodes and Peyer’s patches. It has also been found to be expressed on sinus-lining cells of the spleen. The integrin, alpha 4 beta 7, has been shown to function as the MAdCAM-1 receptor. The Ig domains of MAdCAM-1 have been found to be critical to alpha 4 beta 7 binding. The mucin domain has been shown to have activity in L-Selectin binding.
Images
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Immunohistochemistry of paraffin embedded mouse pancreatic using MADCAM1 (GB111006) at dilution of 1:1700 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse small intestine using MADCAM1 (GB111006) at dilution of 1:1700 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse small intestine using MADCAM1 (GB111006) at dilution of 1:1800 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat colon using MADCAM1 (GB111006) at dilution of 1:1800 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat colon using MADCAM1 (GB111006) at dilution of 1:3400 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat pancreas+LPS using MADCAM1 (GB111006) at dilution of 1:1800 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat pancreas+LPS using MADCAM1 (GB111006) at dilution of 1:3400 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat pancreatic using MADCAM1 (GB111006) at dilution of 1:1700 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat pancreatic using MADCAM1 (GB111006) at dilution of 1:1800 (400x lens) |
 | Immunofluorescence of paraffin embedded human appendix using MADCAM1 (GB111006) at dilution of 1:1800 (400x lens) |
 | Immunofluorescence of paraffin embedded human colon using MADCAM1 (GB111006) at dilution of 1:1800 (400x lens) |
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Immunofluorescence of paraffin embedded human colon using MADCAM1 (GB111006) at dilution of 1:1800 (400x lens) |
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Immunofluorescence of paraffin embedded mouse lung+LPS using MADCAM1 (GB111006) at dilution of 1:1800 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
