Your shopping cart is empty!
Anti-MAdCAM1 Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MAdCAM1 rabbit polyclonal antibody |
Gene Name: | Mucosal addressin cell adhesion molecule 1 |
Synonyms: | MAdCAM-1, mMAdCAM-1, Madcam1, Addressin mucosal, Mucosal vascular addressin cell adhesion molecule 1 |
Immunogen: | Recombinant protein corresponding to Mouse MAdCAM1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 44 kDa |
Observed MW. | 50-60 kDa |
Uniprot ID: | Q13477, Q61826 |
Applications
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 500-1: 1000 | colon |
Background
Lymphocyte recirculation through different organs is thought to be regulated by adhesion molecules ("homing receptors") recognizing tissue-specific vascular addressins on endothelium. The mucosal vascular addressin, MAdCAM1, is an immunoglobulin superfamily adhesion receptor for lymphocytes that is expressed by mucosal venules and helps direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. MAdCAM1 can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes.
Images
|
|
Western blot analysis of MAdCAM1 (GB111347) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
