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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Mediator of RNA polymerase II transcription subunit 4 |
Synonyms: | ARC36, DRIP36, FLJ10956, HSPC126, MED4, mediator complex subunit 4, RP11 90M2.2, TRAP36, VDRIP |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MED4 |
Uniprot ID: | Q9CQA5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 30 kDa / 37 kDa |
Product Usage Information
WB | Human | 1: 500-1: 1000 | Jurkat, A549, K562, Hep G2 |
Background
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors .
Images
| Western blot analysis of MED4 (GB114624) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
