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| Reactivity: | R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MKK6 rabbit polyclonal |
Gene Name: | Dual specificity mitogen-activated protein kinase kinase 6 |
Synonyms: | MAP kinase kinase 6, MAPKK 6, MAPK/ERK kinase 6, MEK 6, SAPKK3, Map2k6, Prkmk6, MAPKK6 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MKK6 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 37 kDa |
Observed MW. | 37 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Rat | 1: 1000-1: 2000 | liver, kidney |
Background
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
Images
 | Western blot analysis of MKK6 (GB113063) at dilution of 1: 2000 Lane 1: Rat liver tissue lysate Lane 2: Rat kidney tissue lysate |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
