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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MLF2 rabbit polyclonal |
Gene Name: | Myeloid leukemia factor 2 |
Synonyms: | Myelodysplasia-myeloid leukemia factor 2, MLF2, NTN4 |
Immunogen: | Recombinant protein corresponding to Mouse MLF2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 28 kDa |
Observed MW. | 28 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, kidney |
Background
Myeloid leukemia factor (MLF) proteins typically demonstrate highest levels of expression in testis, ovary, skeletal muscle, heart, kidney and colon tissues, and lower levels of expression in spleen, thymus, and peripheral blood leukocytes. MLF proteins play a role in normal hemopoietic differentiation as well as in erythroid/myeloid lineage switching. MLF2 is a ubiquitously expressed, 248-amino acid protein which shares 40% sequence identity with myeloid leukemia factor 1 (MLF1). MLF2 maps to chromosome 12p13, a region that is often associated with translocations in acute leukemias of lymphoid and myeloid origin. However, no alterations in the structure of the MLF2 locus in patients shown to have 12p translocations have been discovered.
Images
 | Western blot analysis of MLF2 (GB113248) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
