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Anti-MMP10 Rabbit pAb (100 μl)
| Reactivity: | H & H |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Stromelysin-2 |
Synonyms: | SL-2, Matrix metalloproteinase-10, MMP-10, Transin-2, Mmp10, STMY2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MMP10 |
Uniprot ID: | O55123 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Predicted MW. / Observed MW. | 54 kDa / 54 kDa |
Product Usage Information
WB | Human | 1: 4000-1: 8000 | HepG2, MCF-7 |
IHC/IF | Human | 1: 2400-1: 4800 | cholangiocarcinoma, lung cancer |
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Images
| Western blot analysis of MMP10 (GB112994) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded human cholangiocarcinoma using MMP10 (GB112994) at dilution of 1: 4800 |
| Immunohistochemistry analysis of paraffin-embedded human lung cancer using MMP10 (GB112994) at dilution of 1: 4800 |
| Immunohistochemistry analysis of paraffin-embedded human lung cancer using MMP10 (GB112994) at dilution of 1: 4800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
