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| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MMP2 rabbit polyclonal antibody |
Gene Name: | 72 kDa type IV collagenase |
Synonyms: | MMP2, CLG4, CLG4A, MMP-2, MMP-II, MONA, TBE-1, matrix metallopeptidase 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MMP2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 74 kDa |
Observed MW. | 69 kDa(mature) |
Uniprot ID: | P08253, P33434 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 500-1: 1000 | liver cancer, stomach cancer |
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix(ECM) in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactiveproproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response.
Images
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Western blot analysis of MMP2 (GB111507) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
