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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MMP8 rabbit polyclonal antibody |
Gene Name: | Neutrophil collagenase |
Synonyms: | Mmp8, MMP8, CLG1, HNC, MMP-8, PMNL-CL, Matrix metallopeptidase 8 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MMP8 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 54 kDa |
Observed MW. | 72 kDa |
Uniprot ID: | P22894, O70138, O88766 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | testis, ovary, uterus |
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens.
Images
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Western blot analysis of MMP8 (GB11867) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
