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| Reactivity: | H,M |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MRP1 rabbit polyclonal antibody |
Gene Name: | Multidrug resistance-associated protein 1 |
Synonyms: | ATP-binding cassette sub-family C member 1, Leukotriene C(4) transporter, ABCC1, MRP1, ABCC, LTC4 transporter, ABC29, ABCC 1, GSX, Multidrug resistance associated protein 1, Multidrug resistance protein, MRP, Multiple drug resistance protein 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human MRP1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | P33527 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse | 1: 500-1: 2000 | colon cancer, lung, lung cancer |
Background
Multidrug resistance-associated protein 1 (MRP1) is a protein that in humans is encoded by the ABCC1 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance.
Images
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Immunohistochemistry of paraffin embedded human lung cancer using MRP1 (GB11941) at dilution of 1:1000 (200x lens) |
 | Immunofluorescence of paraffin embedded human colon cancer using MRP1 (GB11941) at dilution of 1:1000 (250x lens) |
 | Immunofluorescence of paraffin embedded human lung cancer using MRP1 (GB11941) at dilution of 1:1000 (250x lens) |
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Immunofluorescence of paraffin embedded mouse lung using MRP1 (GB11941) at dilution of 1:1000 (250x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
