Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | MSH2 rabbit polyclonal |
Gene Name: | DNA mismatch repair protein Msh2 |
Synonyms: | COCA1, FCC1, hMSH2, HNPCC, HNPCC1, LCFS2, MSH2, MutS protein homolog 2, BAT26, MutS homolog 2, MutS homolog 2 colon cancer nonpolyposis type 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MSH2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 104 kDa |
Observed MW. | 104 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | testis, brain, skin |
Background
MSH2, named for its homologous to the E.coli MutS gene, takes part in DNA mismatch repair(MMR) to maintain the stability of DNA. MSH2 contains a helix-turn-helix domain, which responds for binding to DNA. Also, MSH2 has a direct role in mutation avoidance and micro-satellite stability in cell.
Images
Western blot analysis of MSH2 (GB113283) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |