Reactivity: | H,M,R & M,R |
Applications: | WB & IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | MSY2/YBOX2/YBX2 rabbit polyclonal |
Gene Name: | Y-box-binding protein 2 |
Synonyms: | CONTRIN, CSDA3, DBPC, DNA binding protein C, MSY2, MSY2 homolog, Y box binding protein 2, YBX2 |
Immunogen: | Recombinant protein corresponding to Mouse MSY2/YBOX2/YBX2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 38 kDa |
Observed MW. | 55 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | testis, lung |
IHC | Mouse, Rat | 1: 1800-1: 3600 | testis |
Background
MSY2 and YB-2 (MSY3,4) belong to the Y-box family of multifunctional proteins that regulate both transcription and translation (1–3). Y-box proteins interact with a wide variety of nucleic acid structures to act as transcription factors and mRNA masking proteins (1). The modular structure of Y-box proteins includes a highly conserved N-terminal cold-shock domain (CSD, equivalent to the bacterial cold-shock proteins) and four basic C-terminal domains containing arginine clusters and aromatic residues (4). MSY2 is expressed in testis and ovary where it may repress translation of parental mRNA (5,6).
Images
Western blot analysis of Ybx2 (GB113143) at dilution of 1: 2000 | |
Immunohistochemistry analysis of paraffin-embedded mouse testis using Ybx2 (GB113143) at dilution of 1: 3600 | |
Immunohistochemistry analysis of paraffin-embedded rat testis using Ybx2 (GB113143) at dilution of 1: 3600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |