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Anti-MUC20 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MUC20 rabbit polyclonal antibody |
Gene Name: | Mucin-20 |
Synonyms: | MUC-20, KIAA1359, MUC20, Mucin 20 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MUC20 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Secreted |
Uniprot ID: | Q8BUE7 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 1000-1: 2000 | ischemic kidney, liver |
Background
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in most individuals. The allele represented in the human reference assembly contains 12 copies. Multiple transcript variants encoding different isoforms have been found for this gene.
Images
| Immunohistochemistry of paraffin embedded mouse ischemic kidney using MUC20 (GB111965) at dilution of 1:1000 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse liver using MUC20 (GB111965) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
