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| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MVP rabbit polyclonal antibody |
Gene Name: | Major vault protein |
Synonyms: | MVP, LRP, Lung resistance related protein, testicular secretory protein Li 30, VAULT1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MVP |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. | 96 kDa |
Observed MW. | 110 kDa |
Uniprot ID: | Q14764, Q9EQK5, Q62667 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung, colon, pancreas |
IHC/IF | Human, Mouse, Rat | 1: 100-1: 300 | breast, colon, lung |
Background
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.
Images
 | Western blot analysis of LRP (GB112334) at dilution of 1: 500 |
 | Immunofluorescence of paraffin embedded human colon using LRP (GB112334) at dilution of 1: 250 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse lung using LRP (GB112334) at dilution of 1: 250 (400x lens) |
 | Immunofluorescence of paraffin embedded rat breast using LRP (GB112334) at dilution of 1: 250 (400x lens) |
 | Immunofluorescence of paraffin embedded rat lung using LRP (GB112334) at dilution of 1: 200 (250x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
