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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MX2 rabbit polyclonal antibody |
Gene Name: | Interferon-induced GTP-binding protein Mx2 |
Synonyms: | Myxovirus resistance protein 2, Mx2, MXB, MX dynamin like GTPase 2, p78 related protein, Second interferon induced protein p78 |
Immunogen: | Recombinant protein corresponding to Mouse MX2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 74 kDa |
Observed MW. | 74 kDa |
Uniprot ID: | P20592 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | HeLa, 293T, PANC-1, A549, NCI-H1299, A-431, HaCaT |
Background
The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1.
Images
 | Western blot analysis of MX2 (GB112144) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
