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Anti-Myosin VIIa/MYO7A Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Myosin VIIa/MYO7A rabbit polyclonal antibody |
Gene Name: | Unconventional myosin-VIIa |
Synonyms: | Myo7a, Myo7, DFNA11, Deafness autosomal dominant 11, DFNB2, NSRD2, Ush1b, Unconventional myosin VIIa |
Immunogen: | Recombinant protein corresponding to Mouse Myosin VIIa/MYO7A |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 255 kDa |
Observed MW. | 255 kDa |
Uniprot ID: | P97479 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 250-1: 500 | testis |
Background
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. Mediates intracellular transport of RPE65 in the retina pigment epithelium.
Images
| Western blot analysis of Myo7a (GB111997) at dilution of 1: 250 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
