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Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CCL3 rabbit polyclonal antibody |
Gene Name: | C-C motif chemokine 3 |
Synonyms: | Ccl3, CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3, C-C motif chemokine ligand 3, Macrophage Inflammatory Protein 1 alpha, Tonsillar lymphocyte LD78 alpha protein, MIP-1-alpha |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CCL3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 200-1: 800 | hepatitis, pneumonia, spleen, splenitis |
Background
CCL3 is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes through binding to the receptors CCR1, CCR4 and CCR5. CCL3 has been shown to interact with CCL4, and attracts macrophages, monocytes and neutrophils. CCL3 produces a monophasic fever of rapid onset whose magnitude is equal to or greater than that of fevers produced with either recombinant human tumor necrosis factor or recombinant human interleukin-1.
Images
 | Immunohistochemistry of paraffin embedded mouse spleen using ccl3 (GB11687) at dilution of 1:400 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse hepatitis using ccl3 (GB11687) at dilution of 1:400 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse pneumonia using ccl3 (GB11687) at dilution of 1:400 (400x lens) |
 |
Immunofluorescence of paraffin embedded mouse splenitis using ccl3 (GB11687) at dilution of 1:400 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
