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Anti-Mammaglobin A Mouse mAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Mammaglobin-A |
Synonyms: | hMAM, Mammaglobin 1, MGB1, SCGB2A2, UGB2 |
Immunogen: | Recombinant protein corresponding to Human Mammaglobin A |
Uniprot ID: | Q13296 |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Subcellular location: | Secreted, Cytoplasm |
Product Usage Information
IHC/IF | Human | 1: 500-1: 1000 | breast cancer |
Background
Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.
Images
| Immunohistochemistry analysis of paraffin embedded human breast cancer using Mammaglobin A (GB12106) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded human breast cancer using Mammaglobin A (GB12106) at dilution of 1: 500 |
| Immunofluorescence analysis of paraffin embedded human breast cancer using Mammaglobin A (GB12106) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
