Your shopping cart is empty!
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Mre11 rabbit polyclonal antibody |
Gene Name: | Double-strand break repair protein MRE11 |
Synonyms: | Mre11, MRE11, ATLD, HNGS1, MRE11B, MRE11A, MRE11 homolog A, double strand break repair nuclease, MRE11 homolog, double strand break repair nuclease |
Immunogen: | Recombinant protein corresponding to Mouse Mre11 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | P49959 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 500-1: 2000 | breast cancer, colon cancer, gastric cancer, lung cancer, ovarian cancer |
Background
Double-strand break repair protein MRE11A is a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities.
Images
 | Immunohistochemistry of paraffin embedded human breast cancer using Mrel1 (GB11795) at dilution of 1:2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded human gastric cancer using Mrel1 (GB11795) at dilution of 1:2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded human lung cancer using Mrel1 (GB11795) at dilution of 1:2000 (400x lens) |
 |
Immunofluorescence of paraffin embedded human breast cancer using Mrel1 (GB11795) at dilution of 1:1000 (400x lens) |
 |
Immunofluorescence of paraffin embedded human colon cancer using Mrel1 (GB11795) at dilution of 1:1000 (400x lens) |
 |
Immunofluorescence of paraffin embedded human ovarian cancer using Mrel1 (GB11795) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
