Reactivity: | M,R & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Myelin Basic Protein rabbit polyclonal antibody |
Gene Name: | Myelin Basic Protein |
Synonyms: | MBP, entrez:4155, myelin basic protein |
Immunogen: | Recombinant protein corresponding to Mouse Myelin Basic Protein |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Myelin membrane |
Uniprot ID: | P04370, P02688 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 200-1: 2000 | brain, corpus striatum |
Background
The classic group of MBP isoforms (isoform 4-isoform 13) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells.
Images
Immunohistochemistry of paraffin embedded mouse brain using MBP (GB11226-1) at dilution of 1:100 (400x lens) |
|
Immunohistochemistry of paraffin embedded mouse brain using MBP (GB11226-1) at dilution of 1:200 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse corpus striatum using MBP (GB11226-1) at dilution of 1:100 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse corpus striatum using MBP (GB11226-1) at dilution of 1:200 (400x lens) | |
Immunohistochemistry of paraffin embedded rat brain using MBP (GB11226-1) at dilution of 1:200 (400x lens) | |
Immunohistochemistry of paraffin embedded rat corpus striatum using MBP (GB11226-1) at dilution of 1:800 (400x lens) | |
Immunofluorescence of paraffin embedded mouse brain using MBP (GB11226-1) at dilution of 1:100 (400x lens) | |
Immunofluorescence of paraffin embedded mouse brain using MBP (GB11226-1) at dilution of 1:750 (400x lens) | |
Immunofluorescence of paraffin embedded mouse corpus striatum using MBP (GB11226-1) at dilution of 1:100 (400x lens) | |
Immunofluorescence of paraffin embedded mouse corpus striatum using MBP (GB11226-1) at dilution of 1:750 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |