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Anti-Myeloid leukemia factor 1 Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Myeloid leukemia factor 1 rabbit polyclonal antibody |
Gene Name: | Myeloid leukemia factor 1 |
Synonyms: | Hematopoietic lineage switch 7, Myelodysplasia-myeloid leukemia factor 1, Mlf1, Hls7 |
Immunogen: | Recombinant protein corresponding to Mouse Myeloid leukemia factor 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. | 30 kDa |
Observed MW. | 31 kDa |
Uniprot ID: | Q9QWV4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | testis, lung |
IHC/IF | Mouse, Rat | 1: 1000-1: 3000 | lung, testis |
Background
Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Images
| Western blot analysis of MLF1 (GB111634) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded mouse lung using MLF1 (GB111634) at dilution of 1: 1500 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat testis using MLF1 (GB111634) at dilution of 1: 1500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
