Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Myeloperoxidase rabbit polyclonal antibody |
Gene Name: | Myeloperoxidase |
Synonyms: | MPO, myeloperoxidase |
Immunogen: | Recombinant protein corresponding to Mouse Myeloperoxidase |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 84 kDa |
Observed MW. | 60 kDa |
Uniprot ID: | P05164, P11247 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | inflammatory spleen |
Background
Myeloperoxidase (MPO) is a peroxidase enzyme that in humans is encoded by the MPO gene on chromosome 17.MPO is most abundantly expressed in neutrophil granulocytes (a subtype of white blood cells), and produces hypohalous acids to carry out their antimicrobial activity. It is a lysosomal protein stored in azurophilic granules of the neutrophil and released into the extracellular space during degranulation. Neutrophil verdoperoxidase has a heme pigment, which causes its green color in secretions rich in neutrophils, such as pus and some forms of mucus.
Images
Western blot analysis of MPO (GB11224-1) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |