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Anti-Myocilin Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Myocilin rabbit polyclonal |
Gene Name: | Myocilin |
Synonyms: | GLC1A, GPOA, JOAG, JOAG1, MYOC, TIGR, Mutated trabecular meshwork-induced glucocorticoid response protein, Trabecular meshwork induced glucocorticoid response protein |
Immunogen: | Recombinant protein corresponding to Mouse Myocilin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 55 kDa |
Observed MW. | 55 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse | 1: 500-1: 1000 | heart |
Background
Myocilin (MYOC), also known as TIGR or GLC1A, is a secreted glycoprotein of the olfactomedin family, originally identified in trabecular meshwork cells after prolonged treatment with glucocorticoids, and, independently, in the retina . It may participate in the obstruction of fluid outflow in the trabecular meshwork. Defects in MYOC are the cause of primary open angle glaucoma (POAG) .
Images
 | Western blot analysis of Myocilin (GB113162) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
