Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | NACAD rabbit polyclonal antibody |
Gene Name: | NAC-alpha domain-containing protein 1 |
Synonyms: | Nacad, Kiaa0363, NAC Alpha Domain Containing |
Immunogen: | Recombinant protein corresponding to Mouse NACAD |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | O15069, Q5SWP3 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 2000 | brain, eye, spinal cord |
Background
NACAD is a 1,562 amino acid protein that prevents non-secretory polypeptides from targeting the endoplasmic reticulum. Localizing to both the cytoplasm and nucleus, NACAD belongs to the NAC-alpha family and contains one NAC-A/B (NAC-alpha/beta) domain. The gene encoding NACAD maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Images
Immunohistochemistry of paraffin embedded human brain using NACAD (GB112036) at dilution of 1:700 (300x lens) | |
Immunohistochemistry of paraffin embedded mouse eye using NACAD (GB112036) at dilution of 1:1000 (250x lens) | |
Immunohistochemistry of paraffin embedded mouse spinal cord using NACAD (GB112036) at dilution of 1:1000 (400x lens) | |
Immunohistochemistry of paraffin embedded rat eye using NACAD (GB112036) at dilution of 1:1000 (300x lens) | |
Immunohistochemistry of paraffin embedded rat spinal cord using NACAD (GB112036) at dilution of 1:1000 (400x lens) | |
Immunofluorescence of paraffin embedded mouse spinal cord using NACAD (GB112036) at dilution of 1:650 (400x lens) | |
Immunofluorescence of paraffin embedded rat spinal cord using NACAD (GB112036) at dilution of 1:650 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |