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| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | NBR1 rabbit polyclonal antibody |
Gene Name: | Next to BRCA1 gene 1 protein |
Synonyms: | Nbr1, NBR1, 1A1-3B, IAI3B, M17S2, MIG19, neighbor of BRCA1 gene 1, autophagy cargo receptor, NBR1 autophagy cargo receptor |
Immunogen: | Recombinant protein corresponding to Mouse NBR1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: | Q14596 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 500-1: 4000 | colon, colon cancer, gastric cancer, lung cancer, ovarian cancer, prostate |
Background
Proto-oncogene tyrosine-protein kinase Src is a non-receptor tyrosine kinase protein encoded by the SRC gene. This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer.
Images
 | Immunohistochemistry of paraffin embedded human colon using NBR1 (GB11788) at dilution of 1:2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded human gastric cancer using NBR1 (GB11788) at dilution of 1:2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded human lung cancer using NBR1 (GB11788) at dilution of 1:2000 (400x lens) |
 | Immunofluorescence of paraffin embedded human colon cancer using NBR1 (GB11788) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded human gastric cancer using NBR1 (GB11788) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded human ovarian cancer using NBR1 (GB11788) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded human prostate using NBR1 (GB11788) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
