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Anti-NCF1 / p47-phox Rabbit pAb (100 μl)
| Reactivity: | M,R & H,R,M |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Neutrophil cytosol factor 1 |
Synonyms: | Ncf1, NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox, Neutrophil cytosolic factor 1 |
Immunogen: | Recombinant protein corresponding to Mouse NCF1 |
Uniprot ID: | Q09014 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. / Observed MW. | 45 kDa / 47 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | spleen, lung, thymus |
IHC/IF | Human, Mouse, Rat | 1: 1500-1: 6000 | colon, lung, small intestine |
Background
Neutrophil cytosol factor 1, also known as p47phox, is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Genetic variability in the NCF1 gene has been found to be related to a higher chance of getting autoimmune diseases such as Sjögren's syndrome, rheumatoid arthritis and lupus erythematosus.
Images
|
Western blot analysis of p47phox (GB11725) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat hepatitis using p47phox (GB11725) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin embedded rat enteritis using p47phox (GB11725) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin embedded rat colon using p47phox (GB11725) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin embedded mouse small intestine using p47phox (GB11725) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin embedded mouse lung using p47phox (GB11725) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin embedded human colon using p47phox (GB11725) at dilution of 1: 3000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
