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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | NCR1 rabbit polyclonal antibody |
Gene Name: | Natural cytotoxicity triggering receptor 1 |
Synonyms: | Activating receptor 1, mAR-1, Lymphocyte antigen 94, Natural killer cell p46-related protein, NKp46, mNKp46, CD335, Ncr1, Ly94 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse NCR1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 37 kDa |
Observed MW. | 46 kDa |
Uniprot ID: | O76036 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 250-1: 500 | Raji, A-431, THP-1 |
Background
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.When LY94 is expressed in COS-7 cells, anti-NKp46 immunoprecipitates a 46-kD surface molecule. Northern blot analysis revealed weak expression of a major transcript of 3.4 kb in spleen but in no other human tissue. Further analysis, with RT-PCR confirmation, in various lymphoid and myelomonocytic cells revealed that LY94 expression is confined to NK cells.
Images
 | Western blot analysis of NCR1 (GB112140) at dilution of 1: 250 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
