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Anti-NFAT4/NF-ATc3 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | NFATC3 rabbit polyclonal antibody |
Gene Name: | Nuclear factor of activated T-cells, cytoplasmic 3 |
Synonyms: | NF-ATc3, NFATc3, NFATx, NFATC3, NFAT4, T-cell transcription factor NFAT4, NF-AT4, NF-AT4c |
Immunogen: | Recombinant protein corresponding to Mouse NFATC3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 116 kDa |
Observed MW. | 170 kDa |
Uniprot ID: | Q12968 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | HEK293T, Jurkat, HeLa |
Background
NFATc4 (nuclear factor of activated T cells, cytoplasmic, calcineurindependent 4) is a member of the nuclear factors of activated T cells DNAbinding transcription complex that influences cytokine gene expression, cardiac hypertrophy and adipocyte differentiation. NFATc4 has specifically been implicated in vasculature development, regulation of smooth muscle contractile phenotype, and modulation of vascular smooth muscle contractility. NFATc4 plays a role in the inducible expression of cytokine genes in T cells, including the induction of IL-2 and IL-4. p38 MAP kinase phosphorylates multiple residues in the NFAT homology domain of NFATc4.
Images
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Western blot analysis of NFATc3 (GB111453) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
