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Anti-NFkB p100 / NFKB2 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Nuclear factor NF-kappa-B p100 subunit |
Synonyms: | NFKB2, CVID10, H2TF1, LYT-10, LYT10, NF-kB2, p105, p52, p100, p49/p100, nuclear factor kappa B subunit 2, NF-κB |
Immunogen: | Recombinant protein corresponding to Human Nuclear factor NF-kappa-B p100 subunit |
Uniprot ID: | Q00653 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 97 kDa / 100 kDa |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 1000-1: 2000 | HeLa, Jurkat, MCF7 |
Background
NF-κB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NF-κB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
Images
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Western blot analysis of NFKB2 p100 (GB11651) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
