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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | NG2 rabbit polyclonal antibody |
Gene Name: | Chondroitin sulfate proteoglycan 4 |
Synonyms: | Chondroitin sulfate proteoglycan NG2, Proteoglycan AN2, Cspg4, An2, Kiaa4232, Ng2, MSK16, MELCSPG |
Immunogen: | Recombinant protein corresponding to Mouse NG2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 252 kDa |
Observed MW. | 252 kDa |
Uniprot ID: | Q8VHY0, Q00657 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 300-1: 600 | brain, hippocampus |
Background
CSPG4, also named as HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16 and NG2, is a proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. CSPG4 may inhibit neurite outgrowth and growth cone collapse during axon regeneration. It is cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. CSPG4 may regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. It modulates the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin.
Images
| Western blot analysis of NG2 (GB111915) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
