Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | NMDAR1 rabbit polyclonal antibody |
Gene Name: | Glutamate receptor ionotropic, NMDA 1 |
Synonyms: | GRIN1, GluN1, MRD8, NMDA1, NMDAR1, NR1, NMD-R1, glutamate ionotropic receptor NMDA type subunit 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse NMDAR1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cell junction |
Uniprot ID: | P35438 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 100-1: 500 | brain, cerebral infarction, epencephalon |
Background
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.
Images
![]() | Immunohistochemistry of paraffin embedded mouse brain using NMDAR1 (GB11144) at dilution of 1:100 (400x lens) |
![]() | Immunohistochemistry of paraffin embedded rat brain using NMDAR1 (GB11144) at dilution of 1:100 (400x lens) |
![]() | Immunofluorescence of paraffin embedded mouse cerebral infarction using NMDAR1 (GB11144) at dilution of 1:100 (400x lens) |
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Immunofluorescence of paraffin embedded mouse epencephalon using NMDAR1 (GB11144) at dilution of 1:100 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |