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Anti-NOX2/gp91phox Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | NOX2/gp91phox rabbit polyclonal antibody |
Gene Name: | Cytochrome b-245 heavy chain |
Synonyms: | CGD91-phox, Cytochrome b(558) subunit beta, Cytochrome b558 subunit beta, Heme-binding membrane glycoprotein gp91phox, Neutrophil cytochrome b 91 kDa polypeptide, gp91-1, gp91-phox, p22 phagocyte B-cytochrome, Cybb, Cgd |
Immunogen: | Recombinant protein corresponding to Mouse NOX2/gp91phox |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. | 65 kDa |
Observed MW. | 65 kDa |
Uniprot ID: | P04839, Q61093 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 400-1: 800 | liver |
IHC/IF | Human, Mouse, Rat | 1: 650-1: 1300 | lymph node, prefrontal lobe, spleen, tonsil |
Background
NOX2/gp91phox is a critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. It also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.
Images
 | Western blot analysis of gp91phox (GB112362) at dilution of 1: 400 |
 | Immunofluorescence of paraffin embedded human tonsil using gp91phox (GB112362) at dilution of 1: 650 (500x lens) |
 | Immunofluorescence of paraffin embedded mouse lymph node using gp91phox (GB112362) at dilution of 1: 650 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse prefrontal lobe using gp91phox (GB112362) at dilution of 1: 650 (300x lens) |
 | Immunofluorescence of paraffin embedded rat spleen using gp91phox (GB112362) at dilution of 1: 650 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
