Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | NOX2 rabbit polyclonal antibody |
Gene Name: | Cytochrome b-245 heavy chain |
Synonyms: | CYBB, AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, IMD34, NOX2, p91-PHOX |
Immunogen: | Recombinant protein corresponding to Mouse NOX2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | Q61093 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 200-1: 1200 | small intestine, spleen, thymus |
Background
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H+ currents of resting phagocytes.
Images
Immunohistochemistry of paraffin embedded mouse spleen using NOX2 (GB11391) at dilution of 1:200 (400x lens) |
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Immunohistochemistry of paraffin embedded rat spleen using NOX2 (GB11391) at dilution of 1:200 (400x lens) | |
Immunofluorescence of paraffin embedded mouse spleen using NOX2 (GB11391) at dilution of 1:400 (400x lens) | |
Immunofluorescence of paraffin embedded rat small intestine using NOX2 (GB11391) at dilution of 1:400 (400x lens) | |
Immunofluorescence of paraffin embedded rat thymus using NOX2 (GB11391) at dilution of 1:400 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |