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Anti-Nephrin Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Nephrin |
Synonyms: | NPHS1, CNF, NPHN, nephrin, NPHS1 nephrin, nephrin |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Nephrin |
Uniprot ID: | Q9QZS7 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Product Usage Information
IHC/IF | Mouse | 1: 1500-1: 3000 | kidney |
Background
Nephrin is a protein necessary for the proper functioning of the renal filtration barrier. The renal filtration barrier consists of fenestrated endothelial cells, the glomerular basement membrane, and thepodocytes of epithelial cells. Nephrin is a transmembrane protein that is a structural component of the slit diaphragm. They are present on the tips of the podocytes and maintain the normal relationship between the basement membrane and the podocytes of the epithelial cells.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse kidney using Nephrin (GB11343) at dilution of 1:3000. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
