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Anti-Nicotinic Acetylcholine Receptor alpha 7 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CHRNA7 rabbit polyclonal antibody |
Gene Name: | Neuronal acetylcholine receptor subunit alpha-7 |
Synonyms: | Chrna7, Acra7, AChR, 7nAChR, alpha 7 neuronal nicotinic acetylcholine receptor |
Immunogen: | Recombinant protein corresponding to Mouse CHRNA7 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | P49582, Q05941 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 1000-1: 4000 | brain |
Background
Nicotinic acetylcholine receptors (nAChRs) are cholinergic receptors that form ligand-gated ion channels that mediate fast signal transmission at synapses. CHRNA7 (neuronal acetylcholine receptor subunit alpha-7) forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin.
Images
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Immunohistochemistry of paraffin embedded mouse brain using CARNA7 (GB111335) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using CARNA7 (GB111335) at dilution of 1:2000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
