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Anti-Ornithine Carbamoyltransferase/OTC Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | OTC rabbit polyclonal antibody |
Gene Name: | Ornithine carbamoyltransferase, mitochondrial |
Synonyms: | Ornithine transcarbamylase, OTCase, Otc, Ornithine Carbamoyltransferase, Ornithine Carbamoyltransferase |
Immunogen: | Recombinant protein corresponding to Mouse OTC |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 40 kDa |
Observed MW. | 36 kDa |
Uniprot ID: | P11725, P00481 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | liver, small intestine, colon |
Background
This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
Images
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Western blot analysis of OTC (GB111457) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
