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Anti-PABPN1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PABPN1 rabbit polyclonal antibody |
Gene Name: | Polyadenylate-binding protein 2 |
Synonyms: | PABP-2, Poly(A)-binding protein 2, Nuclear poly(A)-binding protein 1, Poly(A)-binding protein II, PABII, Polyadenylate-binding nuclear protein 1, Pabpn1, Pab2, Pabp2 |
Immunogen: | Recombinant protein corresponding to Mouse PABPN1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | Q86U42, Q8CCS6 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 600-1: 3000 | bladder, brain, cervical cancer, colon, colon cancer, gastric cancer, kidney, testis |
Background
This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm.
Images
| Immunohistochemistry of paraffin embedded human cervical cancer using PABPN1 (GB112266) at dilution of 1:600 (400x lens) |
| Immunohistochemistry of paraffin embedded human colon cancer using PABPN1 (GB112266) at dilution of 1:600 (400x lens) |
| Immunohistochemistry of paraffin embedded human gastric cancer using PABPN1 (GB112266) at dilution of 1:600 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse bladder using PABPN1 (GB112266) at dilution of 1:600 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse brain using PABPN1 (GB112266) at dilution of 1:600 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse colon using PABPN1 (GB112266) at dilution of 1:600 (400x lens) |
| Immunohistochemistry of paraffin embedded rat testis using PABPN1 (GB112266) at dilution of 1:600 (300x lens) |
| Immunohistochemistry of paraffin embedded rat bladder using PABPN1 (GB112266) at dilution of 1:600 (400x lens) |
| Immunohistochemistry of paraffin embedded rat brain using PABPN1 (GB112266) at dilution of 1:600 (400x lens) |
| Immunohistochemistry of paraffin embedded rat kidney using PABPN1 (GB112266) at dilution of 1:600 (400x lens) |
| Immunofluorescence of paraffin embedded human cervical cancer using PABPN1 (GB112266) at dilution of 1:600 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse testis using PABPN1 (GB112266) at dilution of 1:600 (300x lens) |
| Immunofluorescence of paraffin embedded mouse kidney using PABPN1 (GB112266) at dilution of 1:600 (400x lens) |
| Immunofluorescence of paraffin embedded rat brain using PABPN1 (GB112266) at dilution of 1:600 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
