Reactivity: | H,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PAPSS1 rabbit polyclonal antibody |
Gene Name: | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 |
Synonyms: | APS kinase, ATP sulfurylase, ATPSK1, PAPS synthase 1, PAPSS, PAPSS 1, PAPSS1, SAT Adenylyl sulfate kinase, SK 1, SK1, Sulfate adenylate transferase, Sulfurylase kinase 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PAPSS1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 71 kDa |
Observed MW. | 71 kDa |
Uniprot ID: | Q60967 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Rat | 1: 300-1: 500 | stomach, testis |
Background
Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway 1, 2, 3, 4. Required for normal biosynthesis of sulfated L-selectin ligands in endothelial cells 5.
Images
Western blot analysis of PAPSS1 (GB113981) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |