Reactivity: | M,R |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PAPSS2 rabbit polyclonal |
Gene Name: | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
Synonyms: | APS kinase, ATP sulfurylase, ATPSK2, PAPS synthase 2, PAPSS 2, PAPSS2, SAT Adenylyl sulfate kinase, SK 2, SK2, Sulfate adenylate transferase, Sulfurylase kinase 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PAPSS2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 70 kDa |
Observed MW. | 70 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 300-1: 600 | liver, kidney |
Background
Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. May have an important role in skeletogenesis during postnatal growth.
Images
Western blot analysis of PAPSS2 (GB113700) at dilution of 1: 600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |