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| Reactivity: | M,R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PARC rabbit polyclonal |
Gene Name: | Cullin-9 |
Synonyms: | CUL-9, p53-associated parkin-like cytoplasmic protein, Cul9, Kiaa0708, Parc |
Immunogen: | Recombinant protein corresponding to Mouse PARC |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 600-1: 1200 | testis, striatum, substantia nigra |
Background
Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5 . Cytoplasmic anchor protein in p53/TP53-associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function.
Images
| Immunohistochemistry analysis of paraffin-embedded mouse testis using PARC (GB113044) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded mouse striatum using PARC (GB113044) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded rat substantia nigra using PARC (GB113044) at dilution of 1: 1200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
