Reactivity: | H,R & H,M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Neuroendocrine convertase 1 |
Synonyms: | BMIQ12, NEC 1, NEC1, Neuroendocrine convertase 1, PC1, PC3, PCSK1, Prohormone convertase 1 |
Immunogen: | Recombinant protein corresponding to Mouse PCSK1 |
Uniprot ID: | P63239 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasmic vesicle |
Predicted MW. / Observed MW. | 84 kDa / 66-74 kDa |
Product Usage Information
WB | Human, Rat | 1: 500-1: 800 | pancreas, pituitary gland |
IHC/IF | Human, Mouse, Rat | 1: 1500-1: 3000 | pancreas |
Background
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
Images
Western blot analysis of PCSK1 (GB114478) at dilution of 1: 500 | |
Immunohistochemistry analysis of paraffin embedded human pancreas using PCSK1 (GB114478) at dilution of 1: 3000 | |
Immunohistochemistry analysis of paraffin embedded rat pancreas using PCSK1 (GB114478) at dilution of 1: 3000 | |
Immunofluorescence analysis of paraffin embedded mouse pancreas using PCSK1 (GB114478) at dilution of 1: 1500 | |
Immunofluorescence analysis of paraffin embedded rat pancreas using PCSK1 (GB114478) at dilution of 1: 1500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |