Your shopping cart is empty!
Anti-PCBP2/hnRNP E2 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PCBP2 rabbit polyclonal antibody |
Gene Name: | Poly(rC)-binding protein 2 |
Synonyms: | PCBP2, Alpha-CP2, Heterogeneous nuclear ribonucleoprotein E2, hnRNP E2, CTBP, Hnrnpx |
Immunogen: | Recombinant protein corresponding to Mouse PCBP2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 39 kDa |
Observed MW. | 39 kDa |
Uniprot ID: | Q15366 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | HeLa, Jurkat, Raji, K562 |
Background
Poly(rC)-binding protein 2 (PCBP2) is a single-stranded nucleic acid binding protein that binds preferentially to oligo dC, It is also named Heterogeneous nuclear ribonucleoprotein E2, binds also poly(rU). It negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation.
Images
|
|
Western blot analysis of PCBP2 (GB111440) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
