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Anti-PCK1/PEPC Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PCK1 rabbit polyclonal antibody |
Gene Name: | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] |
Synonyms: | PEPCK-C, Pck1, PEPC, Phosphoenolpyruvate carboxylase, PEP carboxykinase, MGC22652, Phosphoenolpyruvate carboxykinase 1, Pepck1 |
Immunogen: | Recombinant protein corresponding to Mouse PCK1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 69 kDa |
Observed MW. | 69 kDa |
Uniprot ID: | Q9Z2V4, P07379 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | liver, kidney |
Background
The PCK1 is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
Images
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Western blot analysis of pepck (GB11966) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
